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Multiple subregions within the caveolin-1 scaffolding domain inhibit fibrosis, microvascular leakage, and monocyte migration
The caveolin-1 scaffolding domain (CSD, amino acids 82–101 of caveolin-1) has been shown to suppress bleomycin-induced lung and skin fibrosis and angiotensin II (AngII)-induced myocardial fibrosis. To identify active subregions within CSD, we split its sequence into three slightly overlapping 8-amin...
Autores principales: | Reese, Charles F., Chinnakkannu, Panneerselvam, Tourkina, Elena, Hoffman, Stanley, Kuppuswamy, Dhandapani |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880820/ https://www.ncbi.nlm.nih.gov/pubmed/35213624 http://dx.doi.org/10.1371/journal.pone.0264413 |
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