Cargando…

Analysis of the complete lambda light chain germline usage in patients with AL amyloidosis and dominant heart or kidney involvement

Light chain amyloidosis is one of the most common forms of systemic amyloidosis. The disease is caused by the misfolding and aggregation of immunoglobulin light chains to insoluble fibrils. These fibrils can deposit in different tissues and organs such as heart and kidney and cause organ impairments...

Descripción completa

Detalles Bibliográficos
Autores principales: Berghaus, Natalie, Schreiner, Sarah, Granzow, Martin, Müller-Tidow, Carsten, Hegenbart, Ute, Schönland, Stefan O., Huhn, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880859/
https://www.ncbi.nlm.nih.gov/pubmed/35213605
http://dx.doi.org/10.1371/journal.pone.0264407