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Analysis of the complete lambda light chain germline usage in patients with AL amyloidosis and dominant heart or kidney involvement
Light chain amyloidosis is one of the most common forms of systemic amyloidosis. The disease is caused by the misfolding and aggregation of immunoglobulin light chains to insoluble fibrils. These fibrils can deposit in different tissues and organs such as heart and kidney and cause organ impairments...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880859/ https://www.ncbi.nlm.nih.gov/pubmed/35213605 http://dx.doi.org/10.1371/journal.pone.0264407 |