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Preparation and evaluation of bilayer-core osmotic pump tablets contained topiramate

Topiramate (TPM) was an antiepileptic agent commonly used in clinical. Studies showed that an oral preparation of TPM with extended-release manner could bring some benefits for epileptics. In this paper, controlled release push-pull osmotic pump (PPOP) tablets of sparingly water-soluble TPM were suc...

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Detalles Bibliográficos
Autores principales: Lin, Wen, Li, Yinke, Shi, Qiongzhi, Liao, Xiangru, Zeng, Yuan, Tian, Wei, Xie, Xiangyang, Liu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880887/
https://www.ncbi.nlm.nih.gov/pubmed/35213658
http://dx.doi.org/10.1371/journal.pone.0264457