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TOR complex 2 contributes to regulation of gene expression via inhibiting Gcn5 recruitment to subtelomeric and DNA replication stress genes

The fission yeast TOR complex 2 (TORC2) is required for gene silencing at subtelomeric regions and for the induction of gene transcription in response to DNA replication stress. Thus, TORC2 affects transcription regulation both negatively and positively. Whether these two TORC2-dependent functions s...

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Detalles Bibliográficos
Autores principales: Cohen, Adiel, Pataki, Emese, Kupiec, Martin, Weisman, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880919/
https://www.ncbi.nlm.nih.gov/pubmed/35157728
http://dx.doi.org/10.1371/journal.pgen.1010061