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Extensive age-dependent loss of antibody diversity in naturally short-lived turquoise killifish
Aging individuals exhibit a pervasive decline in adaptive immune function, with important implications for health and lifespan. Previous studies have found a pervasive loss of immune-repertoire diversity in human peripheral blood during aging; however, little is known about repertoire aging in other...
Autores principales: | Bradshaw, William John, Poeschla, Michael, Placzek, Aleksandra, Kean, Samuel, Valenzano, Dario Riccardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8880994/ https://www.ncbi.nlm.nih.gov/pubmed/35129436 http://dx.doi.org/10.7554/eLife.65117 |
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