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Downregulation of PTEN Promotes Autophagy via Concurrent Reduction in Apoptosis in Cardiac Hypertrophy in PPAR α(−/−) Mice

Cardiac hypertrophy is characterized by an increase in the size of the cardiomyocytes which is initially triggered as an adaptive response but ultimately becomes maladaptive with chronic exposure to different hypertrophic stimuli. Prolonged cardiac hypertrophy is often associated with mitochondrial...

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Detalles Bibliográficos
Autores principales: Kumari, Ritu, Ray, Aleepta Guha, Mukherjee, Dibyanti, Chander, Vivek, Kar, Dipak, Kumar, Uppulapu Shravan, Bharadwaj P.V.P., Deepak, Banerjee, Sanjay K., Konar, Aditya, Bandyopadhyay, Arun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881053/
https://www.ncbi.nlm.nih.gov/pubmed/35224041
http://dx.doi.org/10.3389/fcvm.2022.798639