Positional scanning of natural product hispidol’s ring-B: discovery of highly selective human monoamine oxidase-B inhibitor analogues downregulating neuroinflammation for management of neurodegenerative diseases

Multifunctional molecules might offer better treatment of complex multifactorial neurological diseases. Monoaminergic pathways dysregulation and neuroinflammation are common convergence points in diverse neurodegenerative and neuropsychiatric disorders. Aiming to target these diseases, polypharmacol...

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Detalles Bibliográficos
Autores principales: Hassan, Ahmed H. E., Kim, Hyeon Jeong, Gee, Min Sung, Park, Jong-Hyun, Jeon, Hye Rim, Lee, Cheol Jung, Choi, Yeonwoo, Moon, Suyeon, Lee, Danbi, Lee, Jong Kil, Park, Ki Duk, Lee, Yong Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881063/
https://www.ncbi.nlm.nih.gov/pubmed/35196956
http://dx.doi.org/10.1080/14756366.2022.2036737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881063/
https://www.ncbi.nlm.nih.gov/pubmed/35196956
http://dx.doi.org/10.1080/14756366.2022.2036737

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