4-Octyl Itaconate Prevents Free Fatty Acid-Induced Lipid Metabolism Disorder through Activating Nrf2-AMPK Signaling Pathway in Hepatocytes

Nonalcoholic fatty liver disease (NAFLD), characterized with oxidative stress and hepatic steatosis, is a serious threat to human health. As a specific activator of nuclear factor E2-related factor 2 (Nrf2), the 4-octyl itaconate (4-OI) has the beneficial effects in antioxidant and anti-inflammation...

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Detalles Bibliográficos
Autores principales: Chu, Xu, Li, Longlong, Yan, Weiyuan, Ma, Haitian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881125/
https://www.ncbi.nlm.nih.gov/pubmed/35222799
http://dx.doi.org/10.1155/2022/5180242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881125/
https://www.ncbi.nlm.nih.gov/pubmed/35222799
http://dx.doi.org/10.1155/2022/5180242

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