Loss of USP28 and SPINT2 expression promotes cancer cell survival after whole genome doubling

BACKGROUND: Whole genome doubling is a frequent event during cancer evolution and shapes the cancer genome due to the occurrence of chromosomal instability. Yet, erroneously arising human tetraploid cells usually do not proliferate due to p53 activation that leads to CDKN1A expression, cell cycle ar...

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Detalles Bibliográficos
Autores principales: Bernhard, Sara Vanessa, Seget-Trzensiok, Katarzyna, Kuffer, Christian, Krastev, Dragomir B., Stautmeister, Lisa-Marie, Theis, Mirko, Keuper, Kristina, Boekenkamp, Jan-Eric, Kschischo, Maik, Buchholz, Frank, Storchova, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881269/
https://www.ncbi.nlm.nih.gov/pubmed/34962618
http://dx.doi.org/10.1007/s13402-021-00654-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881269/
https://www.ncbi.nlm.nih.gov/pubmed/34962618
http://dx.doi.org/10.1007/s13402-021-00654-5

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