PACS2–TRPV1 axis is required for ER–mitochondrial tethering during ER stress and lung fibrosis

Endoplasmic reticulum (ER) and mitochondria (mito) play a vital role in alveolar type II cell (AEC2) homeostasis and are both stressed in patients with idiopathic pulmonary fibrosis (IPF). Up to now, no data are available with regard to ER–mito cross talk and tethering under conditions of IPF. We he...

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Detalles Bibliográficos
Autores principales: Knoell, Jessica, Chillappagari, Shashi, Knudsen, Lars, Korfei, Martina, Dartsch, Ruth, Jonigk, Danny, Kuehnel, Mark P., Hoetzenecker, Konrad, Guenther, Andreas, Mahavadi, Poornima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881280/
https://www.ncbi.nlm.nih.gov/pubmed/35212819
http://dx.doi.org/10.1007/s00018-022-04189-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881280/
https://www.ncbi.nlm.nih.gov/pubmed/35212819
http://dx.doi.org/10.1007/s00018-022-04189-2

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