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PACS2–TRPV1 axis is required for ER–mitochondrial tethering during ER stress and lung fibrosis
Endoplasmic reticulum (ER) and mitochondria (mito) play a vital role in alveolar type II cell (AEC2) homeostasis and are both stressed in patients with idiopathic pulmonary fibrosis (IPF). Up to now, no data are available with regard to ER–mito cross talk and tethering under conditions of IPF. We he...
Autores principales: | Knoell, Jessica, Chillappagari, Shashi, Knudsen, Lars, Korfei, Martina, Dartsch, Ruth, Jonigk, Danny, Kuehnel, Mark P., Hoetzenecker, Konrad, Guenther, Andreas, Mahavadi, Poornima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881280/ https://www.ncbi.nlm.nih.gov/pubmed/35212819 http://dx.doi.org/10.1007/s00018-022-04189-2 |
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