Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation

Heme metabolism is a key regulator of inflammatory responses. Cobalt protoporphyrin IX (CoPP) is a heme analog and mimic that potently activates the NRF2/heme oxygenase-1 (HO-1) pathway, especially in monocytes and macrophages. We investigated the influence of CoPP on inflammatory responses using a...

Descripción completa

Detalles Bibliográficos
Autores principales: Schaefer, Rachel E. M., Callahan, Rosemary C., Atif, Shaikh M., Orlicky, David J., Cartwright, Ian M., Fontenot, Andrew P., Colgan, Sean P., Onyiah, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881314/
https://www.ncbi.nlm.nih.gov/pubmed/34916594
http://dx.doi.org/10.1038/s41385-021-00474-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881314/
https://www.ncbi.nlm.nih.gov/pubmed/34916594
http://dx.doi.org/10.1038/s41385-021-00474-8

Ejemplares similares