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Disruption of monocyte-macrophage differentiation and trafficking by a heme analog during active inflammation

Heme metabolism is a key regulator of inflammatory responses. Cobalt protoporphyrin IX (CoPP) is a heme analog and mimic that potently activates the NRF2/heme oxygenase-1 (HO-1) pathway, especially in monocytes and macrophages. We investigated the influence of CoPP on inflammatory responses using a...

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Detalles Bibliográficos
Autores principales:	Schaefer, Rachel E. M., Callahan, Rosemary C., Atif, Shaikh M., Orlicky, David J., Cartwright, Ian M., Fontenot, Andrew P., Colgan, Sean P., Onyiah, Joseph C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881314/ https://www.ncbi.nlm.nih.gov/pubmed/34916594 http://dx.doi.org/10.1038/s41385-021-00474-8

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