Cryo-EM structure of translesion DNA synthesis polymerase ζ with a base pair mismatch

The B-family multi-subunit DNA polymerase ζ (Polζ) is important for translesion DNA synthesis (TLS) during replication, due to its ability to extend synthesis past nucleotides opposite DNA lesions and mismatched base pairs. We present a cryo-EM structure of Saccharomyces cerevisiae Polζ with an A:C...

Descripción completa

Detalles Bibliográficos
Autores principales: Malik, Radhika, Johnson, Robert E., Prakash, Louise, Prakash, Satya, Ubarretxena-Belandia, Iban, Aggarwal, Aneel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881453/
https://www.ncbi.nlm.nih.gov/pubmed/35217661
http://dx.doi.org/10.1038/s41467-022-28644-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881453/
https://www.ncbi.nlm.nih.gov/pubmed/35217661
http://dx.doi.org/10.1038/s41467-022-28644-7

Ejemplares similares