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The metabolism of cells regulates their sensitivity to NK cells depending on p53 status

Leukemic cells proliferate faster than non-transformed counterparts. This requires them to change their metabolism to adapt to their high growth. This change can stress cells and facilitate recognition by immune cells such as cytotoxic lymphocytes, which express the activating receptor Natural Kille...

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Detalles Bibliográficos
Autores principales: Belkahla, Sana, Brualla, Joaquin Marco, Fayd’herbe de Maudave, Alexis, Falvo, Paolo, Allende-Vega, Nerea, Constantinides, Michael, Khan, Abrar Ul Haq, Coenon, Lois, Alexia, Catherine, Mitola, Giulia, Massa, Paul, Orecchioni, Stefania, Bertolini, Francesco, Mnif, Wissem, Hernandez, Javier, Anel, Alberto, Villalba, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881467/
https://www.ncbi.nlm.nih.gov/pubmed/35217717
http://dx.doi.org/10.1038/s41598-022-07281-6