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Inhibition of SRP-dependent protein secretion by the bacterial alarmone (p)ppGpp

The stringent response enables bacteria to respond to nutrient limitation and other stress conditions through production of the nucleotide-based second messengers ppGpp and pppGpp, collectively known as (p)ppGpp. Here, we report that (p)ppGpp inhibits the signal recognition particle (SRP)-dependent...

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Detalles Bibliográficos
Autores principales: Czech, Laura, Mais, Christopher-Nils, Kratzat, Hanna, Sarmah, Pinku, Giammarinaro, Pietro, Freibert, Sven-Andreas, Esser, Hanna Folke, Musial, Joanna, Berninghausen, Otto, Steinchen, Wieland, Beckmann, Roland, Koch, Hans-Georg, Bange, Gert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881573/
https://www.ncbi.nlm.nih.gov/pubmed/35217658
http://dx.doi.org/10.1038/s41467-022-28675-0