ATase inhibition rescues age-associated proteotoxicity of the secretory pathway

Malfunction of autophagy contributes to the progression of many chronic age-associated diseases. As such, improving normal proteostatic mechanisms is an active target for biomedical research and a key focal area for aging research. Endoplasmic reticulum (ER)-based acetylation has emerged as a mechan...

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Detalles Bibliográficos
Autores principales: Murie, Maeghan, Peng, Yajing, Rigby, Michael J., Dieterich, Inca A., Farrugia, Mark A., Endresen, Andreas, Bhattacharyya, Anita, Puglielli, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881600/
https://www.ncbi.nlm.nih.gov/pubmed/35217767
http://dx.doi.org/10.1038/s42003-022-03118-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881600/
https://www.ncbi.nlm.nih.gov/pubmed/35217767
http://dx.doi.org/10.1038/s42003-022-03118-0

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