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The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes

Systemic metabolic syndrome significantly increases the risk of morbidity and mortality in patients with non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). However, no effective therapeutic strategies are available, practically because our understanding of its compli...

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Detalles Bibliográficos
Autores principales: Xu, Minxuan, Tan, Jun, Dong, Wei, Zou, Benkui, Teng, Xuepeng, Zhu, Liancai, Ge, Chenxu, Dai, Xianling, Kuang, Qin, Zhong, Shaoyu, Lai, Lili, Yi, Chao, Tang, Tingting, Zhao, Junjie, Wang, Longyan, Liu, Jin, Wei, Hao, Sun, Yan, Yang, Qiufeng, Li, Qiang, Lou, Deshuai, Hu, Linfeng, Liu, Xi, Kuang, Gang, Luo, Jing, Xiong, Mingxin, Feng, Jing, Zhang, Chufeng, Wang, Bochu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881609/
https://www.ncbi.nlm.nih.gov/pubmed/35217669
http://dx.doi.org/10.1038/s41467-022-28641-w