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In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementation
Blastocyst complementation is an intriguing way of generating humanized animals for organ preparation in regenerative medicine and establishing novel models for drug development. Confirming that complemented organs and cells work normally in chimeric animals is critical to demonstrating the feasibil...
Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881621/ https://www.ncbi.nlm.nih.gov/pubmed/35217706 http://dx.doi.org/10.1038/s41598-022-07159-7 |