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In vitro and in vivo functions of T cells produced in complemented thymi of chimeric mice generated by blastocyst complementation

Blastocyst complementation is an intriguing way of generating humanized animals for organ preparation in regenerative medicine and establishing novel models for drug development. Confirming that complemented organs and cells work normally in chimeric animals is critical to demonstrating the feasibil...

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Detalles Bibliográficos
Autores principales: Yamazaki, Kazuto, Kubara, Kenji, Ishii, Satoko, Li, Peng, Dairiki, Ryo, Hihara, Taro, Ishizuka, Yuta, Izumi, Yukina, Kumai, Minoru, Kamisako, Tsutomu, Ishizaki, Hiroyoshi, Sato, Hideyuki, Masaki, Hideki, Mizuno, Naoaki, Mitsuhashi, Kaoru, Ito, Masashi, Hamanaka, Sanae, Yamaguchi, Tomoyuki, Watanabe, Motoo, Sugiyama, Fumihiro, Nakauchi, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881621/
https://www.ncbi.nlm.nih.gov/pubmed/35217706
http://dx.doi.org/10.1038/s41598-022-07159-7