Cargando…

The cap-proximal RNA secondary structure inhibits preinitiation complex formation on HAC1 mRNA

Translation of HAC1 mRNA in the budding yeast Saccharomyces cerevisiae is derepressed when RNase Ire1 removes its intron via nonconventional cytosolic splicing in response to accumulation of unfolded proteins inside the endoplasmic reticulum. The spliced HAC1 mRNA is translated into a transcription...

Descripción completa

Detalles Bibliográficos
Autores principales: Uppala, Jagadeesh Kumar, Sathe, Leena, Chakraborty, Abhijit, Bhattacharjee, Sankhajit, Pulvino, Anthony Thomas, Dey, Madhusudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881652/
https://www.ncbi.nlm.nih.gov/pubmed/35101452
http://dx.doi.org/10.1016/j.jbc.2022.101648