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Small-volume in vitro lipid digestion measurements for assessing drug dissolution in lipid-based formulations using SAXS

Lipid-based formulations improve the absorption capacity of poorly-water-soluble drugs and digestion of the formulation is a critical step in that absorption process. A recent approach to understanding the propensity for drug to dissolve in digesting lipid-based formulations couples an in vitro pH-s...

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Detalles Bibliográficos
Autores principales: Khan, Nafia F., Salim, Malinda, Binte Abu Bakar, Syaza Y., Ristroph, Kurt, Prud'homme, Robert K., Hawley, Adrian, Boyd, Ben J., Clulow, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881665/
https://www.ncbi.nlm.nih.gov/pubmed/35243327
http://dx.doi.org/10.1016/j.ijpx.2022.100113