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Small-volume in vitro lipid digestion measurements for assessing drug dissolution in lipid-based formulations using SAXS
Lipid-based formulations improve the absorption capacity of poorly-water-soluble drugs and digestion of the formulation is a critical step in that absorption process. A recent approach to understanding the propensity for drug to dissolve in digesting lipid-based formulations couples an in vitro pH-s...
Autores principales: | Khan, Nafia F., Salim, Malinda, Binte Abu Bakar, Syaza Y., Ristroph, Kurt, Prud'homme, Robert K., Hawley, Adrian, Boyd, Ben J., Clulow, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881665/ https://www.ncbi.nlm.nih.gov/pubmed/35243327 http://dx.doi.org/10.1016/j.ijpx.2022.100113 |
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