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Peroxisome-generated succinate induces lipid accumulation and oxidative stress in the kidneys of diabetic mice

Diabetes normally causes lipid accumulation and oxidative stress in the kidneys, which plays a critical role in the onset of diabetic nephropathy; however, the mechanism by which dysregulated fatty acid metabolism increases lipid and reactive oxygen species (ROS) formation in the diabetic kidney is...

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Detalles Bibliográficos
Autores principales: Wang, Yaoqing, Zhang, Xiao, Yao, Haoya, Chen, Xiaocui, Shang, Lin, Li, Ping, Cui, Xiaojuan, Zeng, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881667/
https://www.ncbi.nlm.nih.gov/pubmed/35124006
http://dx.doi.org/10.1016/j.jbc.2022.101660