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Peroxisome-generated succinate induces lipid accumulation and oxidative stress in the kidneys of diabetic mice
Diabetes normally causes lipid accumulation and oxidative stress in the kidneys, which plays a critical role in the onset of diabetic nephropathy; however, the mechanism by which dysregulated fatty acid metabolism increases lipid and reactive oxygen species (ROS) formation in the diabetic kidney is...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881667/ https://www.ncbi.nlm.nih.gov/pubmed/35124006 http://dx.doi.org/10.1016/j.jbc.2022.101660 |