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PHLDB2 Mediates Cetuximab Resistance via Interacting With EGFR in Latent Metastasis of Colorectal Cancer

BACKGROUND & AIMS: Latent metastasis of colorectal cancer (CRC) frequently develops months or years after primary surgery, followed by adjuvant therapies, and may progress rapidly even with targeted therapy administered, but the underlying mechanism remains unclear. Here, we aim to explore the m...

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Detalles Bibliográficos
Autores principales: Luo, Maochao, Huang, Zhao, Yang, Xingyue, Chen, Yan, Jiang, Jingwen, Zhang, Lu, Zhou, Li, Qin, Siyuan, Jin, Ping, Fu, Shuyue, Peng, Liyuan, Li, Bowen, Fang, Yongting, Pu, Wenchen, Gong, Yanqiu, Liu, Yu, Ren, Zhixiang, Liu, Qiu-Luo, Wang, Cun, Xiao, Fangqiong, He, Du, Zhang, Hongying, Li, Changlong, Xu, Heng, Dai, Lunzhi, Peng, Yong, Zhou, Zong-Gung, Huang, Canhua, Chen, Hai-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881668/
https://www.ncbi.nlm.nih.gov/pubmed/34952201
http://dx.doi.org/10.1016/j.jcmgh.2021.12.011