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Application of a novel microscopic technique for quantifying CA125 binding to circulating mononuclear cells in longitudinal specimens during treatment for ovarian cancer

BACKGROUND: Measurement of serum CA125, an antigenic fragment of human mucin 16 (MUC16), is used to monitor the clinical progression of epithelial ovarian cancer (EOC). However, rather than simply a passive marker reflecting tumor burden, MUC16 may have a more active role by binding to immune cells...

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Detalles Bibliográficos
Autores principales: Lakatos, Kornél, González, Germán, Hoballah, Jawad, Brooker, Jeff, Jeong, Sinyoung, Evans, Conor, Krauledat, Petra, Hansen, W. Peter, Elias, Kevin M., Patankar, Manish, Fülöp, Vilmos, Konstantinopoulos, Panagiotis A., Cramer, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881808/
https://www.ncbi.nlm.nih.gov/pubmed/35219339
http://dx.doi.org/10.1186/s13048-022-00957-7