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Plasma interleukin-23 and circulating IL-17A(+)IFNγ(+) ex-Th17 cells predict opposing outcomes of anti-TNF therapy in rheumatoid arthritis

OBJECTIVES: TNF-α inhibitors are widely used in rheumatoid arthritis (RA) with varying success. Response to TNF-α inhibition may reflect the evolution of rheumatoid inflammation through fluctuating stages of TNF-α dependence. Our aim was to assess plasma concentrations of Th-17-related cytokines and...

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Detalles Bibliográficos
Autores principales: Millier, Melanie J., Fanning, Niamh C., Frampton, Christopher, Stamp, Lisa K., Hessian, Paul A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8881822/
https://www.ncbi.nlm.nih.gov/pubmed/35219333
http://dx.doi.org/10.1186/s13075-022-02748-3