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p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function

Alzheimer’s disease (AD) and other tauopathies are histopathologically characterized by tau aggregation, along with a chronic inflammatory response driven by microglia. Over the past few years, the role of microglia in AD has been studied mainly in relation to amyloid-β (Aβ) pathology. Consequently,...

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Detalles Bibliográficos
Autores principales: Perea, Juan R., Bolós, Marta, Cuadros, Raquel, García, Esther, García-Escudero, Vega, Hernández, Félix, McManus, Róisín M., Heneka, Michael T., Avila, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882095/
https://www.ncbi.nlm.nih.gov/pubmed/35006531
http://dx.doi.org/10.1007/s12035-021-02715-0