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Fingolimod Rescues Memory and Improves Pathological Hallmarks in the 3xTg-AD Model of Alzheimer’s Disease

Therapeutic strategies for Alzheimer’s disease (AD) have largely focused on the regulation of amyloid pathology while those targeting tau pathology, and inflammatory mechanisms are less explored. In this regard, drugs with multimodal and concurrent targeting of Aβ, tau, and inflammatory processes ma...

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Detalles Bibliográficos
Autores principales: Fagan, Steven G., Bechet, Sibylle, Dev, Kumlesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882098/
https://www.ncbi.nlm.nih.gov/pubmed/35031916
http://dx.doi.org/10.1007/s12035-021-02613-5