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Bax Contributes to Retinal Ganglion Cell Dendritic Degeneration During Glaucoma

The BCL-2 (B-cell lymphoma-2) family of proteins contributes to mitochondrial-based apoptosis in models of neurodegeneration, including glaucomatous optic neuropathy (glaucoma), which degrades the retinal ganglion cell (RGC) axonal projection to the visual brain. Glaucoma is commonly associated with...

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Detalles Bibliográficos
Autores principales: Risner, Michael L., Pasini, Silvia, McGrady, Nolan R., Calkins, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882107/
https://www.ncbi.nlm.nih.gov/pubmed/34984584
http://dx.doi.org/10.1007/s12035-021-02675-5