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Olfactomedin-4 improves cutaneous wound healing by promoting skin cell proliferation and migration through POU5F1/OCT4 and ESR1 signalling cascades

Olfactomedin-4 (OLFM4) is an olfactomedin-domain-containing glycoprotein, which regulates cell adhesion, proliferation, gastrointestinal inflammation, innate immunity and cancer metastasis. In the present study we investigated its role in skin regeneration. We found that OLFM4 expression is transien...

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Detalles Bibliográficos
Autores principales: Klaas, Mariliis, Mäemets-Allas, Kristina, Heinmäe, Elizabeth, Lagus, Heli, Arak, Terje, Eller, Mart, Kingo, Külli, Kankuri, Esko, Jaks, Viljar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882121/
https://www.ncbi.nlm.nih.gov/pubmed/35218417
http://dx.doi.org/10.1007/s00018-022-04202-8