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Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas

Autophagy is an evolutionally conserved catabolic process that degrades cells to maintain homeostasis. Cisplatin-activated autophagy promotes the expression of circ-PKD2, which plays a role as a tumor suppressor gene in the proliferation, migration, and invasion in oral squamous cell carcinoma (OSCC...

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Detalles Bibliográficos
Autores principales: Gao, Ling, Zhang, Qian, Li, Shaoming, Zheng, Jingjing, Ren, Wenhao, Zhi, Keqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882170/
https://www.ncbi.nlm.nih.gov/pubmed/35220397
http://dx.doi.org/10.1038/s41419-021-04497-8