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NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis

Radiation-induced lung injury (RILI) is a common complication of radiotherapy for which no effective interventions are available. NVP-AUY922, a resorcinylic isoxazole amide drug, exhibits anti-inflammatory, immunomodulatory, and therapeutic effects against various types of cancers. In this study, we...

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Detalles Bibliográficos
Autores principales: Li, Li, Wu, Dongming, Deng, Shihua, Li, Jin, Zhang, Feng, Zou, Ye, Zhang, Ting, Xu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882174/
https://www.ncbi.nlm.nih.gov/pubmed/35220409
http://dx.doi.org/10.1038/s41420-022-00887-9