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Dichotomy in hypoxia-induced mitochondrial fission in placental mesenchymal cells during development and preeclampsia: consequences for trophoblast mitochondrial homeostasis

Dynamic changes in physiologic oxygen are required for proper placenta development; yet, when low-oxygen levels persist, placental development is halted, culminating in preeclampsia (PE), a serious complication of pregnancy. Considering mitochondria’s function is intimately linked to oxygen changes,...

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Detalles Bibliográficos
Autores principales: Gillmore, Taylor, Farrell, Abby, Alahari, Sruthi, Sallais, Julien, Kurt, Merve, Park, Chanho, Ausman, Jonathan, Litvack, Michael, Post, Martin, Caniggia, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882188/
https://www.ncbi.nlm.nih.gov/pubmed/35220394
http://dx.doi.org/10.1038/s41419-022-04641-y