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Targeting the Erk1/2 and autophagy signaling easily improved the neurobalst differentiation and cognitive function after young transient forebrain ischemia compared to old gerbils

The hippocampal neurogenesis occurs constitutively throughout adulthood in mammalian species, but declines with age. In this study, we overtly found that the neuroblast proliferation and differentiation in the subgranular zone and the maturation into fully functional and integrated neurons in the gr...

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Detalles Bibliográficos
Autores principales: Wang, Fuxing, Xia, Zihao, Sheng, Peng, Ren, Yu, Liu, Jiajia, Ding, Lidong, Yan, Bing Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882190/
https://www.ncbi.nlm.nih.gov/pubmed/35220404
http://dx.doi.org/10.1038/s41420-022-00888-8