Nutrient-depended metabolic switching during batch cultivation of Streptomyces coelicolor explored with absolute quantitative mass spectrometry-based metabolite profiling

The well-known secondary metabolite-producing bacterium Streptomyces coelicolor is a natural choice for the development of super-hosts optimized for the heterologous expression of antibiotic biosynthetic gene clusters (BGCs). In this study, we used S. coelicolor M145 and its derivative strain M1146...

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Detalles Bibliográficos
Autores principales: Kumar, Kanhaiya, Bruheim, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882213/
https://www.ncbi.nlm.nih.gov/pubmed/35242495
http://dx.doi.org/10.1007/s13205-022-03146-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882213/
https://www.ncbi.nlm.nih.gov/pubmed/35242495
http://dx.doi.org/10.1007/s13205-022-03146-x

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