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Melatonin enhances osteoblastogenesis of senescent bone marrow stromal cells through NSD2‐mediated chromatin remodelling

BACKGROUND: Aging‐associated osteoporosis is frequently seen in the elderly in clinic, but efficient managements are limited because of unclear nosogenesis. The current study aims to investigate the role of melatonin on senescent bone marrow stromal cells (BMSCs) and the underlying regulating mechan...

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Detalles Bibliográficos
Autores principales: Xie, Ying, Han, Na, Li, Feng, Wang, Lijuan, Liu, Gerui, Hu, Meilin, Wang, Sheng, Wei, Xuelei, Guo, Jing, Jiang, Hongmei, Wang, Jingjing, Li, Xin, Wang, Yixuan, Wang, Jingya, Bian, Xiyun, Zhu, Zhongjiao, Zhang, Hui, Liu, Chunhua, Liu, Xiaozhi, Liu, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882236/
https://www.ncbi.nlm.nih.gov/pubmed/35220680
http://dx.doi.org/10.1002/ctm2.746