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LXR agonist improves peripheral neuropathy and modifies PNS immune cells in aged mice

BACKGROUND: Peripheral neuropathy is a common and progressive disorder in the elderly that interferes with daily activities. It is of importance to find efficient treatments to treat or delay this age-related neurodegeneration. Silencing macrophages by reducing foamy macrophages showed significant i...

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Detalles Bibliográficos
Autores principales: Gavini, Chaitanya K., Elshareif, Nadia, Aubert, Gregory, Germanwala, Anand V., Calcutt, Nigel A., Mansuy-Aubert, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882298/
https://www.ncbi.nlm.nih.gov/pubmed/35219337
http://dx.doi.org/10.1186/s12974-022-02423-z