Enrichment Bayesian design for randomized clinical trials using categorical biomarkers and a binary outcome

BACKGROUND: Adaptive clinical trials have been increasingly commonly employed to select a potential target population for one trial without conducting trials separately. Such enrichment designs typically consist of two or three stages, where the first stage serves as a screening process for selectin...

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Detalles Bibliográficos
Autores principales: Vinnat, Valentin, Chevret, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882316/
https://www.ncbi.nlm.nih.gov/pubmed/35220954
http://dx.doi.org/10.1186/s12874-022-01513-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882316/
https://www.ncbi.nlm.nih.gov/pubmed/35220954
http://dx.doi.org/10.1186/s12874-022-01513-z

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