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Enrichment Bayesian design for randomized clinical trials using categorical biomarkers and a binary outcome
BACKGROUND: Adaptive clinical trials have been increasingly commonly employed to select a potential target population for one trial without conducting trials separately. Such enrichment designs typically consist of two or three stages, where the first stage serves as a screening process for selectin...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882316/ https://www.ncbi.nlm.nih.gov/pubmed/35220954 http://dx.doi.org/10.1186/s12874-022-01513-z |