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Evaluation of RevX solution extract as a potential inhibitor of the main protease of SARS-CoV-2—In vitro study and molecular docking

The main protease (M(pro)) of SARS-CoV-2 is a protease necessary for viral polyprotein processing and maturation. M(pro) cleaves the polypeptide sequence after the glutamine residues. There is no known cellular protease with this substrate specificity in humans; therefore, it is considered an attrac...

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Detalles Bibliográficos
Autores principales: Chou, Feng-Pai, Liu, Chia-Chun, Huong Giang, Huynh Nguyet, Huang, Sheng-Cih, Hsu, Hsiu-Fu, Wu, Tung-Kung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882484/
https://www.ncbi.nlm.nih.gov/pubmed/35252620
http://dx.doi.org/10.1016/j.heliyon.2022.e09034