Case Report: Complete Response to Antiangiogenesis and Immune Checkpoint Blockade in an Unresectable MMR-Deficient Leiomyosarcoma Harboring Biallelic Loss of PTEN

BACKGROUND: Leiomyosarcoma (LMS) is a malignant smooth muscle neoplasm, in which the efficacy of immune checkpoint blockade (ICB) is very limited. What is worse, loss of PTEN, known as a negative factor for ICB, frequently occurred in LMS. Seeking new strategies for LMS patients harboring loss of PT...

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Detalles Bibliográficos
Autores principales: Guo, Xi, Li, Suyao, Tong, Hanxing, Zhang, Yong, Ji, Yuan, Zhuang, Rongyuan, Zhang, Chenlu, You, Yang, Lu, Weiqi, Zhou, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882578/
https://www.ncbi.nlm.nih.gov/pubmed/35237514
http://dx.doi.org/10.3389/fonc.2022.802074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882578/
https://www.ncbi.nlm.nih.gov/pubmed/35237514
http://dx.doi.org/10.3389/fonc.2022.802074

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