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Genome-Wide Association Study-Guided Exome Rare Variant Burden Analysis Identifies IL1R1 and CD3E as Potential Autoimmunity Risk Genes for Celiac Disease

Celiac disease (CeD) is a multifactorial autoimmune enteropathy characterized by the overactivation of the immune system in response to dietary gluten. The molecular etiology of CeD is still not well-understood. Therefore, this study aims to identify potential candidate genes involved in CeD pathoge...

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Detalles Bibliográficos
Autores principales: Mansour, Haifa, Banaganapalli, Babajan, Nasser, Khalidah Khalid, Al-Aama, Jumana Yousuf, Shaik, Noor Ahmad, Saadah, Omar Ibrahim, Elango, Ramu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882628/
https://www.ncbi.nlm.nih.gov/pubmed/35237542
http://dx.doi.org/10.3389/fped.2022.837957