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Activation of RARα Receptor Attenuates Neuroinflammation After SAH via Promoting M1-to-M2 Phenotypic Polarization of Microglia and Regulating Mafb/Msr1/PI3K-Akt/NF-κB Pathway

BACKGROUND AND PURPOSE: Subarachnoid hemorrhage (SAH) is a life-threatening subtype of stroke with high rates of mortality. In the early stages of SAH, neuroinflammation is one of the important mechanisms leading to brain injury after SAH. In various central nervous system diseases, activation of RA...

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Detalles Bibliográficos
Autores principales: Tian, Yang, Liu, Binbing, Li, Yuchen, Zhang, Yongzhi, Shao, Jiang, Wu, Pei, Xu, Chao, Chen, Guangduo, Shi, Huaizhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882645/
https://www.ncbi.nlm.nih.gov/pubmed/35237277
http://dx.doi.org/10.3389/fimmu.2022.839796