Adenosine A2A Receptor Suppressed Astrocyte-Mediated Inflammation Through the Inhibition of STAT3/YKL-40 Axis in Mice With Chronic Cerebral Hypoperfusion-induced White Matter Lesions

White matter lesions are an important pathological manifestation of cerebral small vessel disease, with inflammation playing a pivotal role in their development. The adenosine A2a receptor (ADORA2A) is known to inhibit the inflammation mediated by microglia, but its effect on astrocytes is unknown....

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Detalles Bibliográficos
Autores principales: Yuan, Jichao, Chen, Lin, Wang, Jie, Xia, Simin, Huang, Jialu, Zhou, Linke, Feng, Chengjian, Hu, Xiaofei, Zhou, Zhenhua, Ran, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882648/
https://www.ncbi.nlm.nih.gov/pubmed/35237278
http://dx.doi.org/10.3389/fimmu.2022.841290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882648/
https://www.ncbi.nlm.nih.gov/pubmed/35237278
http://dx.doi.org/10.3389/fimmu.2022.841290

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