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Phosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis

Metabolic enzymes have an indispensable role in metabolic reprogramming, and their aberrant expression or activity has been associated with chemosensitivity. Hence, targeting metabolic enzymes remains an attractive approach for treating tumors. However, the influence and regulation of cysteine desul...

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Detalles Bibliográficos
Autores principales: Lin, Jin-Fei, Hu, Pei-Shan, Wang, Yi-Yu, Tan, Yue-Tao, Yu, Kai, Liao, Kun, Wu, Qi-Nian, Li, Ting, Meng, Qi, Lin, Jun-Zhong, Liu, Ze-Xian, Pu, Heng-Ying, Ju, Huai-Qiang, Xu, Rui-Hua, Qiu, Miao-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882671/
https://www.ncbi.nlm.nih.gov/pubmed/35221331
http://dx.doi.org/10.1038/s41392-022-00889-0