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Metabolomic Profiling of Brain Protective Effect of Edaravone on Cerebral Ischemia-Reperfusion Injury in Mice

Edaravone (EDA) injection has been extensively applied in clinics for treating stroke. Nevertheless, the metabolite signatures and underlying mechanisms associated with EDA remain unclear, which deserve further elucidation for improving the accurate usage of EDA. Ischemia stroke was simulated by int...

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Detalles Bibliográficos
Autores principales: Ma, Hui-fen, Zheng, Fan, Su, Lin-jie, Zhang, Da-wei, Liu, Yi-ning, Li, Fang, Zhang, Yuan-yuan, Gong, Shuai-shuai, Kou, Jun-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882761/
https://www.ncbi.nlm.nih.gov/pubmed/35237165
http://dx.doi.org/10.3389/fphar.2022.814942