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CRISPR‐BETS: a base‐editing design tool for generating stop codons

Cytosine base editors (CBEs) can install a predefined stop codon at the target site, representing a more predictable and neater method for creating genetic knockouts without altering the genome size. Due to the enhanced predictability of the editing outcomes, it is also more efficient to obtain homo...

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Detalles Bibliográficos
Autores principales: Wu, Yuechao, He, Yao, Sretenovic, Simon, Liu, Shishi, Cheng, Yanhao, Han, Yangshuo, Liu, Guanqing, Bao, Yu, Fang, Qing, Zheng, Xuelian, Zhou, Jianping, Qi, Yiping, Zhang, Yong, Zhang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882796/
https://www.ncbi.nlm.nih.gov/pubmed/34669232
http://dx.doi.org/10.1111/pbi.13732