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Applied Hepatic Bioengineering: Modeling the Human Liver Using Organoid and Liver-on-a-Chip Technologies

The liver is the most important metabolic hub of endo and xenobiotic compounds. Pre-clinical studies using rodents to evaluate the toxicity of new drugs and cosmetics may produce inconclusive results for predicting clinical outcomes in humans, moreover being banned in the European Union. Human liver...

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Detalles Bibliográficos
Autores principales: Telles-Silva, Kayque Alves, Pacheco, Lara, Komatsu, Sabrina, Chianca, Fernanda, Caires-Júnior, Luiz Carlos, Araujo, Bruno Henrique Silva, Goulart, Ernesto, Zatz, Mayana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8882846/
https://www.ncbi.nlm.nih.gov/pubmed/35237587
http://dx.doi.org/10.3389/fbioe.2022.845360